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Treatments for Peptic Ulcer Disease

The treatment and management of peptic ulcers involves lifestyle changes, medications, alternative and complementary therapies, and surgery. The goals of treatment include:

  • Elimination of Helicobacter pylori infection if present
  • Treating excess bleeding
  • Promoting healing of the ulcer
  • Relieving pain and discomfort
  • Avoiding the development of complications such as perforation, obstruction
  • Preventing ulcer recurrence

Treatment may involve the following:

Lifestyle changesMedicationsAlternative and complementary therapiesSurgery

Revision Information

  • Reviewer: Daus Mahnke, MD
  • Review Date: 12/2016 -
  • Update Date: 05/20/2015 -
  • Meurer LN, Bower DJ. Management of Helicobacter pylori infection. Am Fam Physician. 2002;65(7):1327-36.

  • Peptic ulcer disease. EBSCO DynaMed Plus website. Available at: http://www.dynamed.com/topics/dmp~AN~T116374/Peptic-ulcer-disease. Updated May 11, 2015. Accessed January 12, 2017.

  • Peptic ulcer disease. Merck Manual Professional Version website. Available at: http://www.merckmanuals.com/professional/gastrointestinal-disorders/gastritis-and-peptic-ulcer-disease/peptic-ulcer-disease. Updated May 2014. Accessed January 12, 2017.

  • Peptic ulcers (stomach ulcers). National Institute of Diabetes and Digestive and Kidney Diseases website. Available at: https://www.niddk.nih.gov/health-information/digestive-diseases/peptic-ulcers-stomach-ulcers/all-content. Updated November 2014. Accessed January 12, 2017.

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